I’d say the Queen’s Gambit opening was chosen (for the book) both because it’s quite a catchy title and because the main character is female which the word ‘Queen’ harmonizes with to some extent.
I don’t think we have great Fuseki names for any gender, unless you’re making a film about Shusaku or Kobayashi or something like that.
It’s probably better to just come up with a catchy nickname for the main character and name it that 
Some actual nicknames of players were discussed in this thread Comprehensive list of Pro player's nicknames?, but I’m sure one could make one up for a fictional character.